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Lisinopril falls under the category of ACE inhibitors, which stands for angiotensin-converting enzyme. This enzyme plays a key role in blood pressure regulation by transforming angiotensin I to angiotensin II. When its action is inhibited, blood pressure goes down. The decrease in angiotensin II levels also causes arterioles to relax, further reducing blood pressure. Additionally, Lisinopril affects kidney functions by promoting the removal of sodium and water while enhancing potassium retention, aiding in stabilizing blood pressure.

As for the onset of Lisinopril’s effects on blood pressure, studies suggest that a significant impact is usually observed around an hour post-consumption. The drug’s concentration peaks in the bloodstream approximately 7 hours later. Moreover, its impact lasts a substantial duration, ranging from 24 to 30 hours. Nonetheless, the full potential of this medication typically manifests several weeks into the treatment.


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